Corporate Health in Spain: NAD⁺ & Sirtuin Pathways Driving Longevity & Healthy Aging

    innerbuddies gut microbiome testing

    Corporate Health Reimagined: Harnessing NAD⁺ & Sirtuin Pathways to Drive Longevity & Healthy Aging in the Modern Workplace

    Corporate Health in Spain: NAD⁺ & Sirtuin Pathways Driving Longevity & Healthy Aging

    Science-based employee wellbeing for resilient, high-performing Spanish workplaces

    Corporate Health in Spain is evolving as forward-thinking organizations connect workplace wellbeing with the biology of longevity. By aligning programs to the NAD⁺ and sirtuin pathways, Spanish companies in Madrid, Barcelona, Valencia, and beyond are building cultures that promote sustained energy, cognitive clarity, and healthy aging. This SEO-friendly approach to corporate wellness integrates Spain’s Mediterranean lifestyle advantages with evidence-informed strategies to support the modern workforce and strengthen employer brands.

    NAD⁺ is a fundamental coenzyme involved in cellular energy production, metabolic efficiency, and DNA maintenance, while sirtuins are NAD⁺-dependent proteins that help regulate stress responses, mitochondrial function, and circadian rhythms. Emerging research associates optimized NAD⁺/sirtuin activity with markers linked to longevity and healthy performance. In the context of employee wellbeing programs in Spain, an emphasis on these pathways can support steadier focus, recovery, and resilience—key priorities for HR, Occupational Health, and C‑suite leaders seeking sustainable productivity without compromising safety or compliance.

    Practical, scalable initiatives—grounded in Mediterranean nutrition, quality sleep, smart movement, stress management, daylight exposure, and evidence-informed policies—can encourage NAD⁺ balance and sirtuin-friendly habits in the workplace. Spanish organizations integrating these pillars into corporate health, executive health, and ESG-aligned wellbeing strategies position themselves for improved engagement, talent retention, and long-term vitality. For best outcomes, programs should be tailored to the Spanish workforce, offered bilingually where relevant, and aligned with clinical guidance when discussing any NAD⁺-related interventions, ensuring responsible, measurable, and brand-enhancing healthy aging at work.

    Order a test! Order annual subscription with 2 or 3 tests!
    innerbuddies gut microbiome testing

    From Science to Strategy: Embedding NAD⁺ & Sirtuins in Corporate Health Programs Across Spain

    Actionable frameworks, metrics, and governance for resilient Spanish workplaces

    Translate the science of NAD⁺ and sirtuins into workplace design by optimizing light, meal timing, movement, and recovery protocols. Spanish offices can align circadian support with Mediterranean patterns: earlier, lighter evening meals; polyphenol-rich foods such as extra virgin olive oil, tomatoes, citrus, and grapes; niacin-containing options like legumes and whole grains; and structured hydration. Pair daylight exposure, dynamic workstations, stair prompts, and brief mobility sessions to sustain mitochondrial-efficiency signals and steady energy. Micro-breaks, breathwork, and short mindfulness practices help regulate stress pathways linked to sirtuin activity, supporting focus and resilient performance across high-demand teams.

    Build an evidence-informed measurement stack to make corporate health in Spain accountable. Track leading indicators alongside HR outcomes: sleep quality indices, self-reported vitality and cognitive clarity, optional wearable-derived trends (resting heart rate, HRV), task-switching efficiency, and safe productivity measures, together with absenteeism and presenteeism. Ensure GDPR-compliant governance with informed consent, aggregated reporting, and opt-in participation; collaborate with Occupational Health to interpret results responsibly. Standardize instruments, define a baseline, and review quarterly to refine NAD⁺/sirtuin-aligned interventions without overclaiming effects.

    Operationalize at scale with bilingual resources and role-specific enablement. Equip leaders and managers with playbooks for shift scheduling that respects circadian needs, flexible micro-recovery policies, and meeting hygiene that protects deep work. Align food service, vending, and remote stipends to Mediterranean-nutrition defaults that are sirtuin-friendly; bolster natural light and outdoor meeting norms in Madrid, Barcelona, Valencia, and regional hubs. Craft inclusive pathways for shift, frontline, and hybrid teams so healthy aging practices are accessible to all. When discussing any NAD⁺-related interventions, signpost clinical guidance and encourage employees to consult healthcare professionals as needed.

    Connect wellbeing to strategy and ESG. Framing employee wellbeing programs in Spain around longevity biology elevates employer brand, talent retention, and innovation capacity while reinforcing PRL compliance and the social pillar of ESG. Use a pilot-to-scale playbook: co-create with employees, run an 8–12 week pilot, define clear KPIs and guardrails, then iterate. Communicate wins transparently and cite peer-reviewed evidence where appropriate to maintain trust. Over time, an integrated, NAD⁺- and sirtuin-informed model can cultivate resilient, high-performing Spanish workplaces that deliver sustainable value for people and business.

    Firemní zdraví v České republice: NAD⁺ a Sirtuinové dráhy jako klíč k dlouhověkosti a zdravému stárnutí France Corporate Health: NAD⁺ & Sirtuin Pathways for Longevity & Healthy Aging

    Read more: Corporate Health in Spain—NAD⁺ & Sirtuin Pathways for Longevity

    View more articles

    Get started with Longevity & Healthy Aging in 7 easy steps!

    • 1. Purchase a kit & create an account.

      Do not forget to buy the personalized nutrition advice and the 3-month Noory subscription to get maximum benefit for Longevity & Healthy Aging.

    • 2. Fill in 3 day food diary & survey

      In the survey select "Longevity & Healthy Aging" as your preferred target group. One FREE target group is included with every testkit.

    • 3. Take a stool sample

      And send it back in the return envelope with a prepaid return label. The return logistics and the laboratory process will generally take 3 to 4 weeks.

    • 4. View your results

      Once your results are uploaded and ready, you will receive an email. Login your dashboard to view all analysis results and recommendations. If you also included the nutrition advice and/or the 3-month Noory subscription in your purchase, these will also be available in your dashboard.

    • food recipe platform

      5. Noory platform

      If you bought the 3-month Noory subscription, you will receive direct access to personalized food recipes and meal plans on the Noory platform which AUTOMATICALLY take into account your gut microbiome nutrition advice, your allergies, intolerances and nutritional targets.

      Have ultimate real-time flexibility to choose the food recipes that you prefer to cook and eat. Accessible through desktop or mobile device.

    • health professional

      6. Link your Healthcare Professional (HCP) (optional)

      Both InnerBuddies and Noory are able to provide FREE access to the platform to your healthcare professional. But we need your EXPLICIT consent to do so given all privacy and health regulations. In the InnerBuddies platform you can also download all report sections in PDF format for sharing.

      Noory can also provide HCP access through NooryMed, a remote monitoring platform built for HCP's that allows sharing symptoms, food tracking and also takes into account Food - Drug interactions.

    • retest your gut health

      7. Retest your Gut Microbiome

      After your 3-month Noory subscription has ended, you can perform a new gut microbiome test and hopefully see the desired improvements in your test results. A new gut test will also update your nutrition recommendations and nutritional targets to the Noory platform so that you can start another 3-month improvement process. You can also select a new target group in the InnerBuddies platform if you want to set different objectives for the new 3-month period.

    The InnerBuddies module "Longevity & Healthy Aging" gives you insight in:

    • Gut Microbiome & Short-Chain Fatty Acids (SCFAs)

      SCFAs contribute to anti-inflammation, gut health, and metabolic regulation, all linked to longevity. SCFA's functions as the base mechanism for the other categories. Butyrate gets high weight because of its robust evidence base in inflammation control, gut barrier integrity, and mitochondrial health — all critical for longevity. Propionate pathways are also key, especially for metabolic aging. Acetate is more abundant but generally has broader and more moderate effects; still important, especially as a substrate and signaling molecule.

    • Anti-Inflammatory & Immune Modulation

      Chronic inflammation accelerates aging; these pathways reduce inflammatory markers. Bile acids are among the most potent microbial immunomodulators with systemic relevance (gut-liver-brain axis, mucosal immunity). Tryptophan-derived indoles are among the most potent microbial immunomodulators with systemic relevance (gut-liver-brain axis, mucosal immunity). Polyamines offer both immunomodulatory and cell-protective benefits, especially in aging tissue. LPS and ammonia detox are supportive pathways—critical but more indirect in their effects.

    • Energy Metabolism & Mitochondrial Health

      Efficient energy metabolism supports cellular function, reduces oxidative stress, and enhances lifespan. TCA cycle and ETC dominate due to their centrality in mitochondrial health, bioenergetics, and ROS control — all of which are strongly linked to aging processes. Fat oxidation (FAO) supports metabolic flexibility, ketogenesis, and fasting states — overlapping with caloric restriction benefits. BCAA metabolism is double-edged: essential for mitochondrial function but excessive levels may promote mTOR activation and insulin resistance — balance is critical.

    • Cellular Repair, DNA Protection & Autophagy

      These pathways regulate DNA repair, cellular stress resistance, and autophagy, essential for longevity. Methionine / glutathione gets top weight for direct protection against oxidative stress, a primary driver of DNA damage. NAD⁺ biosynthesis is central to sirtuin-driven longevity mechanisms and DNA repair. Folate supports DNA stability but has more indirect or cofactor-like effects compared to the above.

    • Caloric Restriction & Fasting Mimicry

      Certain pathways mimic the benefits of fasting and caloric restriction, which are linked to lifespan extension.

    Targeted Recommendations

    The module "Longevity & Healthy Aging" provides you with targeted nuttrition recommendations. Targeted not only on your unique gut microbiome but also targeted on the metabolic pathways that, according to the latest scientific publications, are important for Longevity & Healthy Aging.

    • Personalized on the DNA of your own Gut Microbiome

      Receive nutrition recommendations that according to our self-learning algorithms and our large customer database have the highest impact on your own unique gut microbiome.

    • Approved by our Dieticians

      We use Responsible A.I. techniques and built an algorithm that uses both our own proprietary databases but also the knowledge and experience of our strong dietician team.

    • Actionable

      Nutrition recommendations that you can just buy in your local supermarket. For your convenience, we also provide daily dosage recommendations.

    innerbuddies gut microbiome testing

    Focus on your Biological Age and support Longevity & Healthy Aging - Order the gut test that:

    • Provides a score between 0 and 100 of how your gut microbiome composition is optimized for Biological Age / Longevity / Healthy Aging
    • Provides detailed insight in how you rank for each of the microbial metabolic pathways that have been linked to Biological Age / Longevity / Healthy Aging according to the latest scientific publications
    • Uses a cutting-edge and science-based DNA technology
    • Provides you with nutritional and supplement recommendations based on your microbial results that are specifically optimized to lower your Biological Age and support Longevity & Healthy Aging
    • Is developed by an expert team of dieticians, specialists, and scientists to offer you the most accurate gut microbiome analysis
    Start your journey!

    How can InnerBuddies support in reducing your Biological Age and supporting Longevity & Healthy Aging?

    • Improved Digestive Health

      Optimizing the gut microbiome enhances digestion and nutrient absorption, ensuring the body gets vital vitamins and minerals necessary for cellular repair and maintenance, which supports overall health and slows biological aging.

    • Reduced Inflammation

      A balanced gut microbiome helps reduce chronic systemic inflammation—a major driver of aging and age-related diseases—thereby protecting tissues and organs and promoting healthy aging.

    • Enhanced Immune Function

      Gut health directly influences the immune system. Strengthening the microbiome boosts immunity, lowering the risk of infections and age-related immune decline, contributing to longevity.

    • Mental Health and Cognitive Function

      The gut-brain axis connects gut health with brain function. A healthy microbiome can improve mood, reduce anxiety, and support cognitive health, helping maintain mental sharpness with age.

    • Metabolic Health and Weight Management

      Microbiome-based nutrition helps regulate metabolism and blood sugar levels, reducing risks for diabetes and cardiovascular disease, which are linked to accelerated aging.

    • Antioxidant Support and Cellular Repair

      Supplements tailored to the gut microbiome can enhance antioxidant activity and promote cellular repair processes, protecting DNA from damage and slowing biological aging.