Intestinal signaling is the language of the gut-brain axis, coordinating mood, digestion, and overall health. Through a complex dialogue among the enteric nervous system, the vagus nerve, and circulating hormones, the gut communicates with the brain to influence appetite, stress responses, and gut motility. Hormones such as ghrelin, GLP-1, CCK, and peptide YY, along with neural signals, shape how we feel and how efficiently we digest. The microbes living in the gut also participate, generating metabolites and immune messages that modulate this signaling web.
The microbiome is a central conductor of intestinal signaling. Microbes produce neurotransmitters and metabolites that can alter brain chemistry and behavior, while the brain can in turn influence gut function and microbial composition. InnerBuddies offers a comprehensive, modular platform to map and optimize this dialogue. Our Gut Microbiome Health Index provides a 0-to-100 snapshot of gut health, based on an exclusive collaboration with EAFIT University in Colombia, helping quantify the state of intestinal signaling potential in each individual. We also present a top 40 list of bacteria by abundance, comparing your profile to a healthy cohort to illuminate where intestinal signaling may be strongest or needs support.
Going deeper, InnerBuddies categorizes bacterial metabolic functions into positive and negative pathways and shows you how your functional profile stacks up against healthy baselines. This functional lens is especially relevant for understanding and guiding intestinal signaling, since shifts in microbial metabolism can tilt hormone production, neurotransmitter availability, and inflammatory signals. Our Target Group analysis delves into groups like Healthy Aging, Endurance Sport, and Skin & Hair Health, offering insights into which microbiome functions are most relevant for supporting signaling in those contexts. Complement this with personalized nutrition advice derived from 3-day food diaries matched to stool data, giving you diet recommendations that nurture favorable intestinal signaling patterns.
Whether you’re a company looking to power your gut health testing with a white-label solution or a consumer seeking actionable, personalized insights, InnerBuddies has you covered. Our modular Gut Health Operating System brings together nutrition and probiotic/prebiotic guidance, functional pathway insights, and rich reporting to support healthier intestinal signaling. All B2B capabilities are also available directly to consumers, so you can explore a directly customer-facing experience as well. To learn more, explore the microbiome test, subscription options, or partner opportunities through the following pages:
InnerBuddies microbiome test,
InnerBuddies gut health membership,
InnerBuddies partner program.