Host-Microbe Interactions: The Hidden Dialogue Driving Health


Host-microbe interactions form a dynamic dialogue that shapes immunity, digestion, and overall health. These subtle exchanges—microbial metabolites, signaling molecules, and immune cues—guide how our bodies respond to pathogens, how we break down food, and how energy is allocated at the cellular level. By exploring these hidden conversations, we can uncover the levers that promote resilience and wellbeing. To help teams and individuals tune into this dialogue, InnerBuddies offers a white-label Gut Health Operating System that companies can use to power their gut microbiome testing products. At the core, InnerBuddies provides a comprehensive toolkit for decoding host-microbe interactions in actionable terms. The Gut Microbiome Health Index is a 0–100 score that signals the overall health of the gut ecosystem, built on an exclusive IP deal with EAFIT University in Colombia. A top-40 bacteria panel shows abundances for key microbial players and how you compare against a healthy cohort. The platform also categorizes bacterial metabolic functions as positive or negative, so you can see which functional pathways most influence your host-microbe dialogue relative to the healthy reference. Beyond static metrics, InnerBuddies offers Target Group analysis—deep dives into how the gut microbiome scores on pathways most relevant for Healthy Aging, Endurance Sport, Power Sport, Skin & Hair Health, and many other topics. Personalized nutrition advice translates data from 3-day food diaries and stool samples into tailored recommendations. A robust database links individual foods to microbial responses, enabling personalized nutrition and targeted probiotic and prebiotic advice that fits your unique gut signature. And while these are enterprise-grade tools for partners, all the same options are available directly to consumers as well, via the consumer-focused options on the product page or through a subscription plan: InnerBuddies microbiome test and gut health membership. Whether you’re a company seeking to power your own gut-health product or a consumer curious about host-microbe interactions, InnerBuddies brings you closer to the science driving wellness. Discover our consumer options on the product page or start a personalized plan with the subscription page. If you’re exploring partnerships, learn how to collaborate with us on the B2B program and unlock a scalable, white-label solution that powers robust, real-world insights into host-microbe interactions.