16S rRNA vs. Shotgun Sequencing: Which Gut Test Should You Trust? | InnerBuddies
16S rRNA vs. Shotgun Sequencing: Which Gut Test Should You Trust? Our gut is home to trillions of microbes that... Read more
Shotgun metagenomic sequencing quickly unveils microbial diversity, allowing researchers and product teams to see every organism, gene, and function present in a sample. This untargeted approach captures the entire DNA landscape—bacteria, archaea, viruses, and eukaryotes—providing a true panorama of community composition and potential. Compared with targeted assays, shotgun metagenomic sequencing offers higher resolution and discovery power, enabling you to identify rare taxa, assemble genomes, and infer metabolic capabilities. From soil to gut to aquatic systems, it reveals the organisms driving ecosystem processes and their genetic blueprints. With a single sequencing run, shotgun metagenomic sequencing maps not only who is there but what they can do. By cataloging genes and pathways, it helps uncover functional roles—from nutrient cycling and toxin degradation to signaling and stress responses. The data support comparisons across healthy and altered states, track functional shifts over time, and illuminate interactions among microbes. This depth accelerates discovery, guiding targeted interventions that promote resilience, productivity, and balance in complex ecosystems. InnerBuddies harnesses shotgun metagenomic sequencing as the backbone of its white-label Gut Health Operating System. The modular platform translates raw DNA into a suite of consumer-ready insights: a Gut Microbiome Health Index (0-100) built on an exclusive IP deal with EAFIT University in Colombia; abundances for a top-40 bacterial cohort with comparisons to a healthy baseline; and categorized bacterial functions labeled as positive or negative. Our Target Group analysis dives deep into topics like Healthy Aging, Endurance Sport, Skin & Hair Health, and more, showing how functional pathways score within each group. A robust personalized nutrition advice engine uses 3-day food diaries matched to stool data to tailor recommendations, while bespoke probiotic and prebiotic guidance aligns strains with your objectives. And because InnerBuddies serves both consumers and B2B partners, you can deploy the same powerful insights whether you’re selling a gut health test or running a partner program. Ready to see how shotgun metagenomic sequencing can power your product or service? Explore the InnerBuddies ecosystem and start delivering rapid, actionable gut microbiome insights with a white-label platform. Learn more about our consumer Gut Health tests, flexible subscription options, and B2B partnerships: InnerBuddies product page, InnerBuddies subscription page, InnerBuddies B2B page.
16S rRNA vs. Shotgun Sequencing: Which Gut Test Should You Trust? Our gut is home to trillions of microbes that... Read more
Shotgun Metagenomic Test vs 16S: Understanding Microbiome Analysis Methods The human microbiome is a complex community of microorganisms living in... Read more