Measuring Time: Epigenetic and Biological Age Testing for Longevity & Healthy Aging

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    Longevity & Healthy Aging: Personalized Gut Health Solutions

    Measuring Time: Epigenetic and Biological Age Testing for Longevity & Healthy Aging

    Discover your true pace of aging and turn data into daily decisions

    Biological age reflects how your body is functioning today, not just how many birthdays you have celebrated. Modern epigenetic age testing analyzes DNA methylation patterns—sometimes called epigenetic clocks—to estimate your current age trajectory and the pace of aging. Compared with traditional markers, these science-backed biomarkers of aging provide a clearer window into inflammation, metabolic resilience, and cellular repair, helping you align goals for longevity and healthy aging.

    Whether you are starting a personalized longevity plan or optimizing an advanced routine, biological and epigenetic age tests deliver actionable insights. Use them to establish a baseline, track the impact of nutrition, exercise, sleep, stress management, and targeted supplementation, and prioritize interventions that move the needle on healthspan. Because epigenetic changes are dynamic, repeat testing can reveal how lifestyle upgrades influence immune function, cardiometabolic health, and recovery—turning data into sustainable habits.

    What should you look for in a test? Consider validated DNA methylation platforms that report overall biological age, a pace-of-aging score, and category insights (inflammation, metabolic fitness, cognitive and vascular indicators). Pair these results with blood-based biomarkers and wearable metrics for a comprehensive, precision longevity view. By measuring what matters, you can make smarter choices today to support long-term vitality and a longer, stronger life.

    Order a test! Order annual subscription with 2 or 3 tests!
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    From Clock to Compass: Applying Epigenetic Age Insights

    Turn your biological signals into personalized longevity strategy

    Interpreting your biological age and pace of aging starts with context. A lower biological age than your calendar age suggests resilient systems, while a faster pace (>1.0) flags areas for targeted improvement. Focus on trends across re-tests rather than single snapshots, and look for convergence between DNA methylation results and lifestyle inputs. Small, consistent upgrades in nutrition, sleep, movement, and stress skills often shift epigenetic signals more reliably than drastic, short-lived changes—making your test a compass for sustainable healthy aging and lifelong longevity habits.

    Choose validated epigenetic age testing platforms that combine multiple clocks and report both overall biological age and a granular pace-of-aging metric. Consider sample type (saliva vs. blood), lab quality (CLIA/CAP), transparent algorithms, and clear confidence intervals. For actionable comparisons, re-test on a consistent schedule (e.g., every 3–6 months), keeping routines similar before each draw to reduce noise. Privacy matters: favor vendors with explicit data governance, de-identification, and export options so you can integrate results with your broader precision longevity stack.

    Multiply the value of your epigenetic readout by pairing it with complementary biomarkers of aging and wearable metrics. Track inflammation and metabolic resilience (e.g., CRP, fasting glucose, A1c), lipid and vascular indicators (apoB, blood pressure), and fitness signals (VO2max estimates, resting HR, HRV, sleep efficiency). When your DNA methylation age trends younger while cardiometabolic markers improve and recovery metrics stabilize, you gain a high-confidence view of improved healthspan. If results diverge, use the mismatch to refine your plan—tighten nutrition quality, adjust training load, or prioritize sleep and stress regulation.

    Translate insights into a practical playbook: anchor meals around protein and fiber-rich whole foods, emphasize colorful plants and omega-3 sources, and minimize ultra-processed options to support metabolic health and inflammation control. Combine resistance training with aerobic work and daily movement to bolster mitochondrial function and cellular repair. Protect circadian rhythm with consistent sleep and morning light, and build a stress toolkit (breathwork, mindfulness, nature, social connection). Consider targeted supplementation only when indicated by data and professional guidance. Re-test, review trend lines, and iterate—turning objective measures into habits that compound toward long-term vitality and a longer, stronger life.

    Sleep Quality and Circadian Rhythm: A Path to Longevity and Healthy Aging Cardiometabolic Health and Vascular Aging: Advancing Longevity & Healthy Aging

    Find more details about Epigenetic Age & Biological Age Testing

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    Get started with Longevity & Healthy Aging in 7 easy steps!

    • 1. Purchase a kit & create an account.

      Do not forget to buy the personalized nutrition advice and the 3-month Noory subscription to get maximum benefit for Longevity & Healthy Aging.

    • 2. Fill in 3 day food diary & survey

      In the survey select "Longevity & Healthy Aging" as your preferred target group. One FREE target group is included with every testkit.

    • 3. Take a stool sample

      And send it back in the return envelope with a prepaid return label. The return logistics and the laboratory process will generally take 3 to 4 weeks.

    • 4. View your results

      Once your results are uploaded and ready, you will receive an email. Login your dashboard to view all analysis results and recommendations. If you also included the nutrition advice and/or the 3-month Noory subscription in your purchase, these will also be available in your dashboard.

    • food recipe platform

      5. Noory platform

      If you bought the 3-month Noory subscription, you will receive direct access to personalized food recipes and meal plans on the Noory platform which AUTOMATICALLY take into account your gut microbiome nutrition advice, your allergies, intolerances and nutritional targets.

      Have ultimate real-time flexibility to choose the food recipes that you prefer to cook and eat. Accessible through desktop or mobile device.

    • health professional

      6. Link your Healthcare Professional (HCP) (optional)

      Both InnerBuddies and Noory are able to provide FREE access to the platform to your healthcare professional. But we need your EXPLICIT consent to do so given all privacy and health regulations. In the InnerBuddies platform you can also download all report sections in PDF format for sharing.

      Noory can also provide HCP access through NooryMed, a remote monitoring platform built for HCP's that allows sharing symptoms, food tracking and also takes into account Food - Drug interactions.

    • retest your gut health

      7. Retest your Gut Microbiome

      After your 3-month Noory subscription has ended, you can perform a new gut microbiome test and hopefully see the desired improvements in your test results. A new gut test will also update your nutrition recommendations and nutritional targets to the Noory platform so that you can start another 3-month improvement process. You can also select a new target group in the InnerBuddies platform if you want to set different objectives for the new 3-month period.

    The InnerBuddies module "Longevity & Healthy Aging" gives you insight in:

    • Gut Microbiome & Short-Chain Fatty Acids (SCFAs)

      SCFAs contribute to anti-inflammation, gut health, and metabolic regulation, all linked to longevity. SCFA's functions as the base mechanism for the other categories. Butyrate gets high weight because of its robust evidence base in inflammation control, gut barrier integrity, and mitochondrial health — all critical for longevity. Propionate pathways are also key, especially for metabolic aging. Acetate is more abundant but generally has broader and more moderate effects; still important, especially as a substrate and signaling molecule.

    • Anti-Inflammatory & Immune Modulation

      Chronic inflammation accelerates aging; these pathways reduce inflammatory markers. Bile acids are among the most potent microbial immunomodulators with systemic relevance (gut-liver-brain axis, mucosal immunity). Tryptophan-derived indoles are among the most potent microbial immunomodulators with systemic relevance (gut-liver-brain axis, mucosal immunity). Polyamines offer both immunomodulatory and cell-protective benefits, especially in aging tissue. LPS and ammonia detox are supportive pathways—critical but more indirect in their effects.

    • Energy Metabolism & Mitochondrial Health

      Efficient energy metabolism supports cellular function, reduces oxidative stress, and enhances lifespan. TCA cycle and ETC dominate due to their centrality in mitochondrial health, bioenergetics, and ROS control — all of which are strongly linked to aging processes. Fat oxidation (FAO) supports metabolic flexibility, ketogenesis, and fasting states — overlapping with caloric restriction benefits. BCAA metabolism is double-edged: essential for mitochondrial function but excessive levels may promote mTOR activation and insulin resistance — balance is critical.

    • Cellular Repair, DNA Protection & Autophagy

      These pathways regulate DNA repair, cellular stress resistance, and autophagy, essential for longevity. Methionine / glutathione gets top weight for direct protection against oxidative stress, a primary driver of DNA damage. NAD⁺ biosynthesis is central to sirtuin-driven longevity mechanisms and DNA repair. Folate supports DNA stability but has more indirect or cofactor-like effects compared to the above.

    • Caloric Restriction & Fasting Mimicry

      Certain pathways mimic the benefits of fasting and caloric restriction, which are linked to lifespan extension.

    Targeted Recommendations

    The module "Longevity & Healthy Aging" provides you with targeted nuttrition recommendations. Targeted not only on your unique gut microbiome but also targeted on the metabolic pathways that, according to the latest scientific publications, are important for Longevity & Healthy Aging.

    • Personalized on the DNA of your own Gut Microbiome

      Receive nutrition recommendations that according to our self-learning algorithms and our large customer database have the highest impact on your own unique gut microbiome.

    • Approved by our Dieticians

      We use Responsible A.I. techniques and built an algorithm that uses both our own proprietary databases but also the knowledge and experience of our strong dietician team.

    • Actionable

      Nutrition recommendations that you can just buy in your local supermarket. For your convenience, we also provide daily dosage recommendations.

    innerbuddies gut microbiome testing

    Focus on your Biological Age and support Longevity & Healthy Aging - Order the gut test that:

    • Provides a score between 0 and 100 of how your gut microbiome composition is optimized for Biological Age / Longevity / Healthy Aging
    • Provides detailed insight in how you rank for each of the microbial metabolic pathways that have been linked to Biological Age / Longevity / Healthy Aging according to the latest scientific publications
    • Uses a cutting-edge and science-based DNA technology
    • Provides you with nutritional and supplement recommendations based on your microbial results that are specifically optimized to lower your Biological Age and support Longevity & Healthy Aging
    • Is developed by an expert team of dieticians, specialists, and scientists to offer you the most accurate gut microbiome analysis
    Start your journey!

    How can InnerBuddies support in reducing your Biological Age and supporting Longevity & Healthy Aging?

    • Improved Digestive Health

      Optimizing the gut microbiome enhances digestion and nutrient absorption, ensuring the body gets vital vitamins and minerals necessary for cellular repair and maintenance, which supports overall health and slows biological aging.

    • Reduced Inflammation

      A balanced gut microbiome helps reduce chronic systemic inflammation—a major driver of aging and age-related diseases—thereby protecting tissues and organs and promoting healthy aging.

    • Enhanced Immune Function

      Gut health directly influences the immune system. Strengthening the microbiome boosts immunity, lowering the risk of infections and age-related immune decline, contributing to longevity.

    • Mental Health and Cognitive Function

      The gut-brain axis connects gut health with brain function. A healthy microbiome can improve mood, reduce anxiety, and support cognitive health, helping maintain mental sharpness with age.

    • Metabolic Health and Weight Management

      Microbiome-based nutrition helps regulate metabolism and blood sugar levels, reducing risks for diabetes and cardiovascular disease, which are linked to accelerated aging.

    • Antioxidant Support and Cellular Repair

      Supplements tailored to the gut microbiome can enhance antioxidant activity and promote cellular repair processes, protecting DNA from damage and slowing biological aging.