Cardiometabolic Health & Vascular Aging Clinics: Advancing Longevity and Healthy Aging

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    Cardiometabolic Health and Vascular Aging: Advancing Longevity & Healthy Aging

    Cardiometabolic Health & Vascular Aging Clinics: Advancing Longevity and Healthy Aging

    Personalized, prevention-first care for heart, metabolism, and vessels

    Our clinics focus on Cardiometabolic Health and Vascular Aging to help you pursue evidence-based longevity and resilient Healthy Aging. We blend preventive cardiology, metabolic medicine, and lifestyle science to address the drivers of cardiovascular disease, diabetes, and accelerated vascular decline. Through an integrated, data-driven approach, we aim to optimize blood pressure, lipids, glucose control, body composition, and inflammation—key determinants of long-term vitality and healthspan.

    Using advanced assessments, we go beyond routine screening to evaluate arterial stiffness, endothelial function, VO₂ fitness, body composition, and biomarkers linked to insulin resistance and chronic inflammation. This granular risk profiling informs individualized care plans that may include nutrition strategy, physical activity prescription, sleep optimization, stress reduction, and—when appropriate—evidence-based pharmacotherapy. Our goal is precise risk reduction, earlier detection of vascular change, and measurable improvements in cardiometabolic resilience.

    Programs are delivered by a multidisciplinary team leveraging lifestyle medicine, preventive cardiology, and digital tools for continuous monitoring and coaching. Whether you are proactively investing in healthy aging or managing elevated risk, our clinics provide a structured pathway to sustain cardiovascular function, preserve vascular flexibility, and enhance day-to-day performance. Connect with us to explore a personalized roadmap that supports long-term longevity and quality of life.

    Order a test! Order annual subscription with 2 or 3 tests!
    innerbuddies gut microbiome testing

    Precision Cardiometabolic Care for Longevity & Healthy Aging

    Advanced diagnostics, personalized interventions, and measurable outcomes

    Building on our prevention-first model, we deploy an integrated diagnostic stack to illuminate your unique cardiometabolic risk profile. Beyond routine labs, assessments may include arterial stiffness metrics (pulse wave velocity, augmentation index), endothelial function testing (e.g., FMD/PAT), cardiorespiratory fitness via CPET for VO₂ and heart-rate recovery, and body composition with DXA to quantify visceral adiposity and lean mass. Targeted biomarkers—ApoB, Lp(a), hs-CRP, fasting insulin, CGM-derived glycemic variability, and liver fat risk indicators—help pinpoint drivers of insulin resistance, dyslipidemia, and chronic inflammation. When appropriate, imaging such as carotid IMT or coronary calcium scoring can refine risk and guide the intensity of prevention.

    Using this granular map, we co-create a personalized plan that blends nutrition strategy, movement, recovery, and (when clinically indicated) pharmacotherapy. Nutrition emphasizes minimally processed, fiber-rich patterns (e.g., Mediterranean/DASH), smart carbohydrate quality for glucose stability, balanced protein distribution to protect muscle, and cardioprotective fats to optimize lipids and inflammation. Training programs integrate Zone 2 aerobic conditioning for mitochondrial health, progressive resistance training to preserve strength and insulin sensitivity, and time-efficient intervals as tolerated. We pair these with sleep optimization, stress modulation informed by HRV, and support for tobacco cessation and alcohol moderation—core pillars for sustainable Healthy Aging.

    Where evidence supports added benefit, clinicians may layer targeted therapies to accelerate risk reduction—such as statins/ezetimibe/PCSK9 inhibitors for elevated ApoB, antihypertensives to normalize blood pressure load, or agents like SGLT2 inhibitors and GLP-1 receptor agonists for cardio-renal-metabolic protection—always individualized and monitored. Our iterative model tracks meaningful endpoints: time-in-range on CGM, ambulatory blood pressure, ApoB and triglyceride/HDL ratio, VO₂ and strength progression, arterial stiffness and endothelial function trends, and inflammation markers. The goal is clear: slow Vascular Aging, enhance resilience, and extend functional healthspan without over-treatment.

    Programs are tailored to life stage and context—proactive prevention, metabolic syndrome or prediabetes, women’s cardiometabolic health (including perimenopause/menopause), weight management, athletic longevity, and post-event stabilization. Expect a structured pathway: an initial deep-dive assessment, a 90-day implementation sprint with digital coaching and remote monitoring, then quarterly optimization cycles. With transparent metrics and shared decision-making, you’ll see how daily choices shape Cardiometabolic Health over time. Connect with our team to design a personalized roadmap that preserves vascular flexibility, protects the heart and metabolism, and advances your long-term longevity and quality of life.

    Corporate Health: Cardiometabolic Wellness & Vascular Aging for Longevity & Healthy Aging in the Workplace Next-Gen Leaders in Cardiometabolic Health & Vascular Aging: Paving the Path to Longevity & Healthy Aging

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    Get started with Longevity & Healthy Aging in 7 easy steps!

    • 1. Purchase a kit & create an account.

      Do not forget to buy the personalized nutrition advice and the 3-month Noory subscription to get maximum benefit for Longevity & Healthy Aging.

    • 2. Fill in 3 day food diary & survey

      In the survey select "Longevity & Healthy Aging" as your preferred target group. One FREE target group is included with every testkit.

    • 3. Take a stool sample

      And send it back in the return envelope with a prepaid return label. The return logistics and the laboratory process will generally take 3 to 4 weeks.

    • 4. View your results

      Once your results are uploaded and ready, you will receive an email. Login your dashboard to view all analysis results and recommendations. If you also included the nutrition advice and/or the 3-month Noory subscription in your purchase, these will also be available in your dashboard.

    • food recipe platform

      5. Noory platform

      If you bought the 3-month Noory subscription, you will receive direct access to personalized food recipes and meal plans on the Noory platform which AUTOMATICALLY take into account your gut microbiome nutrition advice, your allergies, intolerances and nutritional targets.

      Have ultimate real-time flexibility to choose the food recipes that you prefer to cook and eat. Accessible through desktop or mobile device.

    • health professional

      6. Link your Healthcare Professional (HCP) (optional)

      Both InnerBuddies and Noory are able to provide FREE access to the platform to your healthcare professional. But we need your EXPLICIT consent to do so given all privacy and health regulations. In the InnerBuddies platform you can also download all report sections in PDF format for sharing.

      Noory can also provide HCP access through NooryMed, a remote monitoring platform built for HCP's that allows sharing symptoms, food tracking and also takes into account Food - Drug interactions.

    • retest your gut health

      7. Retest your Gut Microbiome

      After your 3-month Noory subscription has ended, you can perform a new gut microbiome test and hopefully see the desired improvements in your test results. A new gut test will also update your nutrition recommendations and nutritional targets to the Noory platform so that you can start another 3-month improvement process. You can also select a new target group in the InnerBuddies platform if you want to set different objectives for the new 3-month period.

    The InnerBuddies module "Longevity & Healthy Aging" gives you insight in:

    • Gut Microbiome & Short-Chain Fatty Acids (SCFAs)

      SCFAs contribute to anti-inflammation, gut health, and metabolic regulation, all linked to longevity. SCFA's functions as the base mechanism for the other categories. Butyrate gets high weight because of its robust evidence base in inflammation control, gut barrier integrity, and mitochondrial health — all critical for longevity. Propionate pathways are also key, especially for metabolic aging. Acetate is more abundant but generally has broader and more moderate effects; still important, especially as a substrate and signaling molecule.

    • Anti-Inflammatory & Immune Modulation

      Chronic inflammation accelerates aging; these pathways reduce inflammatory markers. Bile acids are among the most potent microbial immunomodulators with systemic relevance (gut-liver-brain axis, mucosal immunity). Tryptophan-derived indoles are among the most potent microbial immunomodulators with systemic relevance (gut-liver-brain axis, mucosal immunity). Polyamines offer both immunomodulatory and cell-protective benefits, especially in aging tissue. LPS and ammonia detox are supportive pathways—critical but more indirect in their effects.

    • Energy Metabolism & Mitochondrial Health

      Efficient energy metabolism supports cellular function, reduces oxidative stress, and enhances lifespan. TCA cycle and ETC dominate due to their centrality in mitochondrial health, bioenergetics, and ROS control — all of which are strongly linked to aging processes. Fat oxidation (FAO) supports metabolic flexibility, ketogenesis, and fasting states — overlapping with caloric restriction benefits. BCAA metabolism is double-edged: essential for mitochondrial function but excessive levels may promote mTOR activation and insulin resistance — balance is critical.

    • Cellular Repair, DNA Protection & Autophagy

      These pathways regulate DNA repair, cellular stress resistance, and autophagy, essential for longevity. Methionine / glutathione gets top weight for direct protection against oxidative stress, a primary driver of DNA damage. NAD⁺ biosynthesis is central to sirtuin-driven longevity mechanisms and DNA repair. Folate supports DNA stability but has more indirect or cofactor-like effects compared to the above.

    • Caloric Restriction & Fasting Mimicry

      Certain pathways mimic the benefits of fasting and caloric restriction, which are linked to lifespan extension.

    Targeted Recommendations

    The module "Longevity & Healthy Aging" provides you with targeted nuttrition recommendations. Targeted not only on your unique gut microbiome but also targeted on the metabolic pathways that, according to the latest scientific publications, are important for Longevity & Healthy Aging.

    • Personalized on the DNA of your own Gut Microbiome

      Receive nutrition recommendations that according to our self-learning algorithms and our large customer database have the highest impact on your own unique gut microbiome.

    • Approved by our Dieticians

      We use Responsible A.I. techniques and built an algorithm that uses both our own proprietary databases but also the knowledge and experience of our strong dietician team.

    • Actionable

      Nutrition recommendations that you can just buy in your local supermarket. For your convenience, we also provide daily dosage recommendations.

    innerbuddies gut microbiome testing

    Focus on your Biological Age and support Longevity & Healthy Aging - Order the gut test that:

    • Provides a score between 0 and 100 of how your gut microbiome composition is optimized for Biological Age / Longevity / Healthy Aging
    • Provides detailed insight in how you rank for each of the microbial metabolic pathways that have been linked to Biological Age / Longevity / Healthy Aging according to the latest scientific publications
    • Uses a cutting-edge and science-based DNA technology
    • Provides you with nutritional and supplement recommendations based on your microbial results that are specifically optimized to lower your Biological Age and support Longevity & Healthy Aging
    • Is developed by an expert team of dieticians, specialists, and scientists to offer you the most accurate gut microbiome analysis
    Start your journey!

    How can InnerBuddies support in reducing your Biological Age and supporting Longevity & Healthy Aging?

    • Improved Digestive Health

      Optimizing the gut microbiome enhances digestion and nutrient absorption, ensuring the body gets vital vitamins and minerals necessary for cellular repair and maintenance, which supports overall health and slows biological aging.

    • Reduced Inflammation

      A balanced gut microbiome helps reduce chronic systemic inflammation—a major driver of aging and age-related diseases—thereby protecting tissues and organs and promoting healthy aging.

    • Enhanced Immune Function

      Gut health directly influences the immune system. Strengthening the microbiome boosts immunity, lowering the risk of infections and age-related immune decline, contributing to longevity.

    • Mental Health and Cognitive Function

      The gut-brain axis connects gut health with brain function. A healthy microbiome can improve mood, reduce anxiety, and support cognitive health, helping maintain mental sharpness with age.

    • Metabolic Health and Weight Management

      Microbiome-based nutrition helps regulate metabolism and blood sugar levels, reducing risks for diabetes and cardiovascular disease, which are linked to accelerated aging.

    • Antioxidant Support and Cellular Repair

      Supplements tailored to the gut microbiome can enhance antioxidant activity and promote cellular repair processes, protecting DNA from damage and slowing biological aging.