The Role of Polyphenols in Gut Wellness
Polyphenols are plant compounds found in foods such as berries, apples, tea, cocoa, nuts and herbs. In the gut, some interact with resident microbes and are transformed into smaller metabolites; research suggests these processes may influence microbial activity and gut function. Eating a varied, plant-rich diet is a practical way to include them, but polyphenols are not a treatment for digestive conditions.
What Are Polyphenols?
Polyphenols are a broad group of naturally occurring compounds. Major types include flavonoids, such as anthocyanins in berries and catechins in tea; phenolic acids, found in foods including coffee and some fruits; and other groups such as lignans in flaxseed and ellagitannins in pomegranate and walnuts. The amount and type vary with the food, variety, ripeness, storage and preparation.
How Polyphenols Interact with Gut Microbes
Some polyphenols are absorbed in the small intestine, while others reach the colon, where gut microbes can break them down into metabolites. This two-way interaction may:
- Influence the activity and balance of gut microbial communities.
- Produce metabolites that can be used or further transformed by the body.
- Work alongside dietary fiber, which gut microbes ferment into short-chain fatty acids (SCFAs).
Effects differ between people and foods, and findings about particular microbes or health outcomes do not establish that a food prevents or treats disease. Polyphenols are also distinct from probiotics, which are live microorganisms, and prebiotics, which are substances selectively used by microorganisms and confer a health benefit. Some plant foods provide fermentable fiber as well as polyphenols, but the terms are not interchangeable.