One Health Microbiome Framework: A Unified Path to Health


Discover the One Health Microbiome Framework: a unified path to health bridging humans, animals, and the environment to guide research, policy, and prevention. This framework treats the microbiome as a shared interface where host biology, animal health, and ecological conditions interact, enabling cross-disciplinary insights. By aligning data standards, surveillance, and translational pipelines, it supports coordinated action from scientists, regulators, and practitioners. In a world where zoonotic risks and environmental shifts challenge public health, the One Health Microbiome Framework offers a practical roadmap for prevention and resilience. It emphasizes three pillars: integrated data ecosystems, cross-sector collaboration, and actionable translation. As a One Health Microbiome Framework, it harmonizes data streams from clinical samples, livestock, wildlife, and environmental sources to reveal patterns that span species and habitats. The framework translates discoveries into research priorities, risk assessments, and policy guidance, helping to prevent disease spillovers, optimize agricultural practices, and safeguard ecosystem services. By focusing on prevention rather than reaction, the framework aligns science with tangible health outcomes for people, animals, and the planet. Within this framework, practical platforms like InnerBuddies provide modular microbiome measurement and interpretation that can power both research and consumer health products. InnerBuddies offers a white-label Gut Health Operating System that companies can use to power their gut microbiome testing products. It features a Gut Microbiome Health Index—an exclusive 0–100 score developed under an IP deal with EAFIT University in Colombia—along with a top 40 bacteria list showing abundances against a healthy cohort. It also catalogs bacterial metabolic functions, labeling each as positive or negative, and allows target-group analyses for Healthy Aging, Endurance Sport, Skin & Hair Health, and more. The system delivers personalized nutrition advice by correlating three-day food diaries with stool data, and it provides personalized probiotic and prebiotic recommendations. Moreover, InnerBuddies makes all of its B2B options accessible directly to consumers, expanding reach and impact. Learn more on the product page: InnerBuddies microbiome test and for ongoing engagement, see the subscription option: InnerBuddies gut health membership. For partners looking to scale, the B2B program is here: InnerBuddies B2B partner program. By integrating such technologies within the One Health Microbiome Framework, researchers and policymakers can translate microbiome insights into interventions that benefit humans, animals, and ecosystems alike. Whether you are advancing public health surveillance, optimizing animal husbandry, or protecting environmental integrity, this framework helps align goals, metrics, and actions across sectors. Explore how the One Health Microbiome Framework can guide your work and connect with InnerBuddies to bring microbiome insights from research to real-world prevention and health optimization across domains.